mouse PARL shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Parl.
shAAV-280961
AAV-m-PARL-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Parl (presenilin associated, rhomboid-like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D16Ertd607e; PRO2207; Psarl; PSARL1; PSENIP2
Description (Vector)
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
Gene ID
381038
Gene Name (Vector)
presenilin associated, rhomboid-like
Gene Symbol
Parl
ORF Size (aa)
1134
ORF Size (bp)
1134 bp
RefSeq ID
NM_001005767
RefSeq Synonyms
NM_001005767, BC083153,
Species
mouse
UniGene ID
Mm.371737
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.