mouse NCOA3 shRNA silencing AAV

Name 
AAV-m-NCOA3-shRNA
Cat No 
shAAV-280906
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ncoa3.

shAAV-280906
AAV-m-NCOA3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ncoa3 (nuclear receptor coactivator 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010305B15Rik; Actr; Aib1; AW321064; bHLHe42; KAT13B; p/Cip; pCip; Rac3; Src3; Tram-1; Tram1
Description (Vector)
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. Interacts with PSMB9.
Gene ID
17979
Gene Name (Vector)
nuclear receptor coactivator 3
Gene Symbol
Ncoa3
ORF Size (aa)
4212
ORF Size (bp)
4212 bp
RefSeq ID
NM_008679
RefSeq Synonyms
NM_008679, BC141177, BC086482,
Species
mouse
UniGene ID
Mm.476883

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.