mouse KLF17 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Klf17.
shAAV-280833
AAV-m-KLF17-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Klf17 (Kruppel-like factor 17). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; Gzf; Zfp393
Description (Vector)
Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).
Gene ID
75753
Gene Name (Vector)
Kruppel-like factor 17
Gene Symbol
Klf17
ORF Size (aa)
1026
RefSeq ID
NM_029416
RefSeq Synonyms
NM_029416, BC064748,
Species
mouse
UniGene ID
Mm.3848
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.