mouse UGT1A1 shRNA silencing AAV

Name
AAV-m-UGT1A1-shRNA

Cat No
shAAV-278232

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Ugt1a1.

shAAV-278232

AAV-m-UGT1A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ugt1a1 (UDP glucuronosyltransferase 1 family, polypeptide A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gnt1; UDPGT 1-1; Udpgt-1a; UGT1A01; UgtBr1

Description (Vector)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.

Gene ID

394436

Gene Name (Vector)

UDP glucuronosyltransferase 1 family, polypeptide A1

Gene Symbol

Ugt1a1

ORF Size (aa)

1608

ORF Size (bp)

1608 bp

RefSeq ID

NM_201645

RefSeq Synonyms

NM_201645, BC093516,

Species

mouse

UniGene ID

Mm.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.