mouse HSPA1A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hspa1a.
shAAV-277566
AAV-m-HSPA1A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hspa1a (heat shock protein 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hsp68; Hsp70-3; Hsp70.3; hsp70A1; Hsp72
Description (Vector)
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Gene ID
193740
Gene Name (Vector)
heat shock protein 1A
Gene Symbol
Hspa1a
ORF Size (aa)
1926
ORF Size (bp)
1926 bp
RefSeq ID
NM_010479
RefSeq Synonyms
NM_010479, BC054782,
Species
mouse
UniGene ID
Mm.6388
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.