mouse TDRD3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tdrd3.
shAAV-277430
AAV-m-TDRD3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tdrd3 (tudor domain containing 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732418C03Rik; 6720468N18
Description (Vector)
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
Gene ID
219249
Gene Name (Vector)
tudor domain containing 3
Gene Symbol
Tdrd3
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
RefSeq ID
NM_172605
RefSeq Synonyms
NM_172605, NM_001253755, BC066144, BC005670,
Species
mouse
UniGene ID
Mm.35168
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.