mouse ZWINT shRNA silencing AAV

Name
AAV-m-ZWINT-shRNA

Cat No
shAAV-277165

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Zwint.

shAAV-277165

AAV-m-ZWINT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Zwint (ZW10 interactor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2010007E07Rik; 2600001N01Rik; D10Ertd749e; Zwint-1

Description (Vector)

Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.

Gene ID

52696

Gene Name (Vector)

ZW10 interactor

Gene Symbol

Zwint

ORF Size (aa)

759

RefSeq ID

NM_025635

RefSeq Synonyms

NM_025635, NM_001293684, NM_001293683, BC034870, BC027100,

Species

mouse

UniGene ID

Mm.62876

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.