mouse ZFYVE20 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rbsn.
shAAV-277045
AAV-m-ZFYVE20-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rbsn (rabenosyn, RAB effector). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5330426D11Rik; Zfyve20
Description (Vector)
Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
Gene ID
78287
Gene Name (Vector)
rabenosyn, RAB effector
Gene Symbol
Rbsn
ORF Size (aa)
2352
ORF Size (bp)
2352 bp
RefSeq ID
NM_030081
RefSeq Synonyms
NM_030081, BC049106, BC031135,
Species
mouse
UniGene ID
Mm.290734
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.