mouse ZFP57 shRNA silencing AAV

Name 
AAV-m-ZFP57-shRNA
Cat No 
shAAV-276897
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Zfp57.

shAAV-276897
AAV-m-ZFP57-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Zfp57 (zinc finger protein 57). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
G19; Zfp-57
Description (Vector)
Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells.
Gene ID
22715
Gene Name (Vector)
zinc finger protein 57
Gene Symbol
Zfp57
ORF Size (aa)
1266
RefSeq ID
NM_001013745
RefSeq Synonyms
NM_001168502, NM_001168501, NM_001013745, BC052028,
Species
mouse
UniGene ID
Mm.305561

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.