mouse XPA shRNA silencing AAV

Name 
AAV-m-XPA-shRNA
Cat No 
shAAV-276401
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Xpa.

shAAV-276401
AAV-m-XPA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Xpa (xeroderma pigmentosum, complementation group A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI573865; Xpac
Description (Vector)
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Gene ID
22590
Gene Name (Vector)
xeroderma pigmentosum, complementation group A
Gene Symbol
Xpa
ORF Size (aa)
840
ORF Size (bp)
840 bp
RefSeq ID
NM_011728
RefSeq Synonyms
NM_011728, BC029241,
Species
mouse
UniGene ID
Mm.247036

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.