mouse WDR77 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Wdr77.
shAAV-276239
AAV-m-WDR77-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Wdr77 (WD repeat domain 77). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610003I18Rik; 2610312E17Rik; C79984; p44/MEP50
Description (Vector)
Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Gene ID
70465
Gene Name (Vector)
WD repeat domain 77
Gene Symbol
Wdr77
ORF Size (aa)
1029
ORF Size (bp)
1029 bp
RefSeq ID
NM_027432
RefSeq Synonyms
NM_027432, BC005755,
Species
mouse
UniGene ID
Mm.5110
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.