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mouse WAPAL shRNA silencing AAV

Name 
AAV-m-WAPAL-shRNA
Cat No 
shAAV-276127
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Wapl.

shAAV-276127
AAV-m-WAPAL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Wapl (WAPL cohesin release factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A530089A20Rik; BC037674; DIF-2; FOE; Wapal
Description (Vector)
Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Gene ID
218914
Gene Name (Vector)
WAPL cohesin release factor
Gene Symbol
Wapl
ORF Size (aa)
3585
ORF Size (bp)
3585 bp
RefSeq ID
NM_001004436
RefSeq Synonyms
NM_001301330, NM_001004436, BC145625, BC139434,
Species
mouse
UniGene ID
Mm.27957

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.