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mouse VWF shRNA silencing AAV

Name 
AAV-m-VWF-shRNA
Cat No 
shAAV-276123
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Vwf.

shAAV-276123
AAV-m-VWF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Vwf (Von Willebrand factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6820430P06Rik; AI551257; B130011O06Rik; C630030D09; F8VWF; VWD
Description (Vector)
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Gene ID
22371
Gene Name (Vector)
Von Willebrand factor
Gene Symbol
Vwf
ORF Size (aa)
8439
ORF Size (bp)
8439 bp
RefSeq ID
NM_011708
RefSeq Synonyms
NM_011708, BC148363,
Species
mouse
UniGene ID
Mm.22339

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.