mouse VTA1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Vta1.
shAAV-276104
AAV-m-VTA1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Vta1 (vesicle (multivesicular body) trafficking 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110001D18Rik; 1110059P08Rik; AU040813; C85340; LIP5; SBP1
Description (Vector)
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
Gene ID
66201
Gene Name (Vector)
vesicle (multivesicular body) trafficking 1
Gene Symbol
Vta1
ORF Size (aa)
930
ORF Size (bp)
930 bp
RefSeq ID
NM_025418
RefSeq Synonyms
NM_025418, BC026752,
Species
mouse
UniGene ID
Mm.227983
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.