mouse VCAM1 shRNA silencing AAV

Name
AAV-m-VCAM1-shRNA

Cat No
shAAV-275983

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Vcam1.

shAAV-275983

AAV-m-VCAM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Vcam1 (vascular cell adhesion molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD106; Vcam-1

Description (Vector)

Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

Gene ID

22329

Gene Name (Vector)

vascular cell adhesion molecule 1

Gene Symbol

Vcam1

ORF Size (aa)

2220

ORF Size (bp)

2220 bp

RefSeq ID

NM_011693

RefSeq Synonyms

NM_011693, BC029823, BC011159,

Species

mouse

UniGene ID

Mm.440909

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.