mouse DNAJA3 shRNA silencing AAV

Name 
AAV-m-DNAJA3-shRNA
Cat No 
shAAV-275968
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dnaja3.

shAAV-275968
AAV-m-DNAJA3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dnaja3 (DnaJ heat shock protein family (Hsp40) member A3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1200003J13Rik; 1810053A11Rik; C81173; Tid-1; Tid1l
Description (Vector)
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
Gene ID
83945
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member A3
Gene Symbol
Dnaja3
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_023646
RefSeq Synonyms
NM_023646, NM_001135112, BC027240,
Species
mouse
UniGene ID
Mm.248337

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.