mouse USP48 shRNA silencing AAV

Name
AAV-m-USP48-shRNA

Cat No
shAAV-275749

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Usp48.

shAAV-275749

AAV-m-USP48-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Usp48 (ubiquitin specific peptidase 48). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2810449C13Rik; AI115503; BC021769; D330022K21Rik; Usp31

Description (Vector)

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at post-synaptic sites.

Gene ID

170707

Gene Name (Vector)

ubiquitin specific peptidase 48

Gene Symbol

Usp48

ORF Size (aa)

3156

ORF Size (bp)

3156 bp

RefSeq ID

NM_130879

RefSeq Synonyms

NM_130879, NM_001347227, BC148642,

Species

mouse

UniGene ID

Mm.218478

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.