mouse USP46 shRNA silencing AAV

Name 
AAV-m-USP46-shRNA
Cat No 
shAAV-275747
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Usp46.

shAAV-275747
AAV-m-USP46-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Usp46 (ubiquitin specific peptidase 46). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
76
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1190009E20Rik; 2410018I08Rik; AI451644
Description (Vector)
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
Gene ID
69727
Gene Name (Vector)
ubiquitin specific peptidase 46
Gene Symbol
Usp46
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_177561
RefSeq Synonyms
NM_177561, BC039916,
Species
mouse
UniGene ID
Mm.473866

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.