mouse USP44 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Usp44.
shAAV-275745
AAV-m-USP44-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Usp44 (ubiquitin specific peptidase 44). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E430004F17Rik
Description (Vector)
Deubiquitinase that plays a key role in the spindle checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint), thereby preventing premature activation of the APC/C.
Gene ID
327799
Gene Name (Vector)
ubiquitin specific peptidase 44
Gene Symbol
Usp44
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
RefSeq ID
NM_183199
RefSeq Synonyms
NM_183199, NM_001206851, BC111886,
Species
mouse
UniGene ID
Mm.276331
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.