mouse USP21 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Usp21.
shAAV-275722
AAV-m-USP21-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Usp21 (ubiquitin specific peptidase 21). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ESTM28; Usp16; Usp23; W53272
Description (Vector)
Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates.
Gene ID
30941
Gene Name (Vector)
ubiquitin specific peptidase 21
Gene Symbol
Usp21
ORF Size (aa)
1701
ORF Size (bp)
1701 bp
RefSeq ID
NM_013919
RefSeq Synonyms
NM_013919, BC021903,
Species
mouse
UniGene ID
Mm.27510
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.