mouse UPK3B shRNA silencing AAV

Name
AAV-m-UPK3B-shRNA

Cat No
shAAV-275672

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Upk3b.

shAAV-275672

AAV-m-UPK3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Upk3b (uroplakin 3B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI447729; AI957187; P35; PMS2L14; UpIIIb

Description (Vector)

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).

Gene ID

100647

Gene Name (Vector)

uroplakin 3B

Gene Symbol

Upk3b

ORF Size (aa)

831

ORF Size (bp)

831 bp

RefSeq ID

NM_175309

RefSeq Synonyms

NM_175309, BC137742, BC120594,

Species

mouse

UniGene ID

Mm.402943

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.