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mouse UNC84A shRNA silencing AAV

Name 
AAV-m-UNC84A-shRNA
Cat No 
shAAV-275644
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sun1.

shAAV-275644
AAV-m-UNC84A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sun1 (Sad1 and UNC84 domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4632417G13Rik; 5730434D03Rik; mKIAA0810; Unc84a
Description (Vector)
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes (NPCs) (By similarity).
Gene ID
77053
Gene Name (Vector)
Sad1 and UNC84 domain containing 1
Gene Symbol
Sun1
ORF Size (aa)
2742
ORF Size (bp)
2742 bp
RefSeq ID
NM_024451
RefSeq Synonyms
NM_024451, NM_001256118, NM_001256117, NM_001256116, NM_001256115, BC048156, BC047928,
Species
mouse
UniGene ID
Mm.210845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.