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mouse UGCGL1 shRNA silencing AAV

Name 
AAV-m-UGCGL1-shRNA
Cat No 
shAAV-275586
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Uggt1.

shAAV-275586
AAV-m-UGCGL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Uggt1 (UDP-glucose glycoprotein glucosyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0910001L17Rik; A930007H10Rik; AA589501; AI414429; AI448372; C820010P03Rik; GT; Ugcgl1; UGT1
Description (Vector)
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Gene ID
320011
Gene Name (Vector)
UDP-glucose glycoprotein glucosyltransferase 1
Gene Symbol
Uggt1
ORF Size (aa)
4656
ORF Size (bp)
4656 bp
RefSeq ID
NM_198899
RefSeq Synonyms
NM_198899, BC068283, BC062936,
Species
mouse
UniGene ID
Mm.392153

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.