mouse UBASH3B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ubash3b.
shAAV-275453
AAV-m-UBASH3B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ubash3b (ubiquitin associated and SH3 domain containing, B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810457I06Rik; BB125008; p70; TULA-2
Description (Vector)
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
Gene ID
72828
Gene Name (Vector)
ubiquitin associated and SH3 domain containing, B
Gene Symbol
Ubash3b
ORF Size (aa)
1917
ORF Size (bp)
1917 bp
RefSeq ID
NM_176860
RefSeq Synonyms
NM_176860, BC053436,
Species
mouse
UniGene ID
Mm.133615
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.