mouse UBA6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Uba6.
shAAV-275443
AAV-m-UBA6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Uba6 (ubiquitin-like modifier activating enzyme 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930542H01; 5730469D23Rik; AU021846; AW124799; E1-L2; Ube1l2
Description (Vector)
Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
Gene ID
231380
Gene Name (Vector)
ubiquitin-like modifier activating enzyme 6
Gene Symbol
Uba6
ORF Size (aa)
3162
ORF Size (bp)
3162 bp
RefSeq ID
NM_172712
RefSeq Synonyms
NM_172712, BC063048,
Species
mouse
UniGene ID
Mm.440954
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.