mouse UACA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Uaca.
shAAV-275428
AAV-m-UACA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Uaca (uveal autoantigen with coiled-coil domains and ankyrin repeats). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2700059D02Rik; nucling
Description (Vector)
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity)|Function: Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
Gene ID
72565
Gene Name (Vector)
uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene Symbol
Uaca
ORF Size (aa)
4242
ORF Size (bp)
4242 bp
RefSeq ID
NM_028283
RefSeq Synonyms
NM_028283, BC042415, BC033470,
Species
mouse
UniGene ID
Mm.68819
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.