mouse U2AF1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse U2af1.
shAAV-275419
AAV-m-U2AF1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2010107D16Rik; 35kDa
Description (Vector)
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Gene ID
108121
Gene Name (Vector)
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
Gene Symbol
U2af1
ORF Size (aa)
720
RefSeq ID
NM_024187
RefSeq Synonyms
NM_024187, NM_001163769, BC115480, BC115479,
Species
mouse
UniGene ID
Mm.379289
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.