mouse TRPV1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Trpv1.
shAAV-275106
AAV-m-TRPV1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Trpv1 (transient receptor potential cation channel, subfamily V, member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1
Description (Vector)
Receptor-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. May be involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity).
Gene ID
193034
Gene Name (Vector)
transient receptor potential cation channel, subfamily V, member 1
Gene Symbol
Trpv1
ORF Size (aa)
2520
ORF Size (bp)
2520 bp
RefSeq ID
NM_001001445
RefSeq Synonyms
NM_001001445, BC153199, BC148644,
Species
mouse
UniGene ID
Mm.447485
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.