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mouse TNRC4 shRNA silencing AAV

Name 
AAV-m-TNRC4-shRNA
Cat No 
shAAV-274782
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Celf3.

shAAV-274782
AAV-m-TNRC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Celf3 (CUGBP, Elav-like family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4930415M08Rik; BRUNOL1; CAGH4; ERDA4; Tnrc4
Description (Vector)
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Gene ID
78784
Gene Name (Vector)
CUGBP, Elav-like family member 3
Gene Symbol
Celf3
ORF Size (aa)
1485
ORF Size (bp)
1485 bp
RefSeq ID
NM_172434
RefSeq Synonyms
NM_172434, NM_001289620, NM_001289616, NM_001289613, BC057553,
Species
mouse
UniGene ID
Mm.44292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.