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mouse TNFSF12 shRNA silencing AAV

Name 
AAV-m-TNFSF12-shRNA
Cat No 
shAAV-274724
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tnfsf12.

shAAV-274724
AAV-m-TNFSF12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfsf12 (tumor necrosis factor (ligand) superfamily, member 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
68
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Apo3l; Dr3l; Dr3lg; Tweak
Description (Vector)
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
Gene ID
21944
Gene Name (Vector)
tumor necrosis factor (ligand) superfamily, member 12
Gene Symbol
Tnfsf12
ORF Size (aa)
747
ORF Size (bp)
747 bp
RefSeq ID
NM_011614
RefSeq Synonyms
NM_011614, BC152795,
Species
mouse
UniGene ID
Mm.8983

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.