mouse TNFSF11 shRNA silencing AAV

Name
AAV-m-TNFSF11-shRNA

Cat No
shAAV-274722

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Tnfsf11.

shAAV-274722

AAV-m-TNFSF11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfsf11 (tumor necrosis factor (ligand) superfamily, member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ly109l; ODF; OPGL; RANKL; Trance

Description (Vector)

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Gene ID

21943

Gene Name (Vector)

tumor necrosis factor (ligand) superfamily, member 11

Gene Symbol

Tnfsf11

ORF Size (aa)

951

ORF Size (bp)

951 bp

RefSeq ID

NM_011613

RefSeq Synonyms

NM_011613, BC131970, BC125603,

Species

mouse

UniGene ID

Mm.249221

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.