mouse TLE4 shRNA silencing AAV

Name 
AAV-m-TLE4-shRNA
Cat No 
shAAV-274263
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tle4.

shAAV-274263
AAV-m-TLE4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tle4 (transducin-like enhancer of split 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5730411M05Rik; AA792082; Bce-1; Bce1; ESTM13; ESTM14; grg-4; Grg4; X83332; X83333
Description (Vector)
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Gene ID
21888
Gene Name (Vector)
transducin-like enhancer of split 4
Gene Symbol
Tle4
ORF Size (aa)
2322
ORF Size (bp)
2322 bp
RefSeq ID
NM_011600
RefSeq Synonyms
NM_011600, NM_001302951, NM_001302950, NM_001302947, BC165993,
Species
mouse
UniGene ID
Mm.103638

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.