mouse TIMP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Timp1.
shAAV-274229
AAV-m-TIMP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Timp1 (tissue inhibitor of metalloproteinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Clgi; EPA; Timp; TIMP-1; TPA-S1
Description (Vector)
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
Gene ID
21857
Gene Name (Vector)
tissue inhibitor of metalloproteinase 1
Gene Symbol
Timp1
ORF Size (aa)
618
ORF Size (bp)
618 bp
RefSeq ID
NM_011593
RefSeq Synonyms
NM_011593, NM_001294280, NM_001044384, BC051260, BC034260, BC008107,
Species
mouse
UniGene ID
Mm.8245
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.