mouse TFB2M shRNA silencing AAV

Name
AAV-m-TFB2M-shRNA

Cat No
shAAV-274081

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Tfb2m.

shAAV-274081

AAV-m-TFB2M-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tfb2m (transcription factor B2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Hkp1

Description (Vector)

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Gene ID

15278

Gene Name (Vector)

transcription factor B2, mitochondrial

Gene Symbol

Tfb2m

ORF Size (aa)

1191

ORF Size (bp)

1191 bp

RefSeq ID

NM_008249

RefSeq Synonyms

NM_008249, NM_001331055, NM_001331054, BC138837, BC138836,

Species

mouse

UniGene ID

Mm.293529

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.