mouse TDRD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tdrd1.
shAAV-273995
AAV-m-TDRD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tdrd1 (tudor domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MTR-1
Description (Vector)
Plays a central role during spermatogenesis by participating in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).
Gene ID
83561
Gene Name (Vector)
tudor domain containing 1
Gene Symbol
Tdrd1
ORF Size (aa)
2787
ORF Size (bp)
2787 bp
RefSeq ID
NM_031387
RefSeq Synonyms
NM_031387, NM_001002241, NM_001002240, NM_001002238, BC129955, BC129954,
Species
mouse
UniGene ID
Mm.247541
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.