mouse TAF1C shRNA silencing AAV

Name 
AAV-m-TAF1C-shRNA
Cat No 
shAAV-273651
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Taf1c.

shAAV-273651
AAV-m-TAF1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Taf1c (TATA-box binding protein associated factor, RNA polymerase I, C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mTAFI95; Tafi95
Description (Vector)
Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Gene ID
21341
Gene Name (Vector)
TATA-box binding protein associated factor, RNA polymerase I, C
Gene Symbol
Taf1c
ORF Size (aa)
2511
ORF Size (bp)
2511 bp
RefSeq ID
NM_021441
RefSeq Synonyms
NM_021441, BC058383,
Species
mouse
UniGene ID
Mm.41977

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.