mouse SRXN1 shRNA silencing AAV

Name 
AAV-m-SRXN1-shRNA
Cat No 
shAAV-273166
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Srxn1.

shAAV-273166
AAV-m-SRXN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Srxn1 (sulfiredoxin 1 homolog (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1700127B04Rik; AI854065; AW488194; Npn3; Srx; Srx1; TX01
Description (Vector)
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
Gene ID
76650
Gene Name (Vector)
sulfiredoxin 1 homolog (S. cerevisiae)
Gene Symbol
Srxn1
ORF Size (aa)
411
RefSeq ID
NM_029688
RefSeq Synonyms
NM_029688, BC049957, BC011325,
Species
mouse
UniGene ID
Mm.218639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.