mouse SPRY4 shRNA silencing AAV

Name 
AAV-m-SPRY4-shRNA
Cat No 
shAAV-273096
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Spry4.

shAAV-273096
AAV-m-SPRY4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Spry4 (sprouty homolog 4 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A030006O18Rik; sprouty4
Description (Vector)
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Gene ID
24066
Gene Name (Vector)
sprouty homolog 4 (Drosophila)
Gene Symbol
Spry4
ORF Size (aa)
903
RefSeq ID
NM_011898
RefSeq Synonyms
NM_011898, BC057005, BC050944,
Species
mouse
UniGene ID
Mm.42038

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.