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mouse SPON2 shRNA silencing AAV

Name 
AAV-m-SPON2-shRNA
Cat No 
shAAV-273053
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Spon2.

shAAV-273053
AAV-m-SPON2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Spon2 (spondin 2, extracellular matrix protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310045I24Rik; AI504350; M-spondin; Mindin; Mspondin
Description (Vector)
Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS).
Gene ID
100689
Gene Name (Vector)
spondin 2, extracellular matrix protein
Gene Symbol
Spon2
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_133903
RefSeq Synonyms
NM_133903, BC017616,
Species
mouse
UniGene ID
Mm.34694

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.