mouse SPN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Spn.
shAAV-273029
AAV-m-SPN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Spn (sialophorin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A630014B01Rik; Cd43; Galgp; Ly-48; Ly48
Description (Vector)
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Gene ID
20737
Gene Name (Vector)
sialophorin
Gene Symbol
Spn
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_009259
RefSeq Synonyms
NM_009259, NM_001037810, BC100741, BC100740, BC100739, BC100738,
Species
mouse
UniGene ID
Mm.283714
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.