mouse SPDYA shRNA silencing AAV

Name
AAV-m-SPDYA-shRNA

Cat No
shAAV-272973

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Spdya.

shAAV-272973

AAV-m-SPDYA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Spdya (speedy/RINGO cell cycle regulator family, member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4921517J08Rik; 4930548B21Rik; GS4; MLZ-465; Spdy1

Description (Vector)

Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2.

Gene ID

70891

Gene Name (Vector)

speedy/RINGO cell cycle regulator family, member A

Gene Symbol

Spdya

ORF Size (aa)

852

RefSeq ID

NM_029254

RefSeq Synonyms

NM_029254, NM_001142631, BC147719, BC147706,

Species

mouse

UniGene ID

Mm.477599

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.