mouse SNX9 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Snx9.
shAAV-272826
AAV-m-SNX9-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Snx9 (sorting nexin 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2700073N08Rik; SDP1; SH3PX1
Description (Vector)
SNX9 may be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.
Gene ID
66616
Gene Name (Vector)
sorting nexin 9
Gene Symbol
Snx9
ORF Size (aa)
1788
ORF Size (bp)
1788 bp
RefSeq ID
NM_025664
RefSeq Synonyms
NM_025664, BC014814,
Species
mouse
UniGene ID
Mm.89515
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.