mouse SNX18 shRNA silencing AAV

Name 
AAV-m-SNX18-shRNA
Cat No 
shAAV-272797
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Snx18.

shAAV-272797
AAV-m-SNX18-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Snx18 (sorting nexin 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Snag1
Description (Vector)
SNX18 may be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
Gene ID
170625
Gene Name (Vector)
sorting nexin 18
Gene Symbol
Snx18
ORF Size (aa)
1848
ORF Size (bp)
1848 bp
RefSeq ID
NM_130796
RefSeq Synonyms
NM_130796, BC145951, BC137801, BC063089,
Species
mouse
UniGene ID
Mm.33721

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.