mouse SMOX shRNA silencing AAV

Name 
AAV-m-SMOX-shRNA
Cat No 
shAAV-272656
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Smox.

shAAV-272656
AAV-m-SMOX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Smox (spermine oxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B130066H01Rik; PAO; PAOh1; SMO
Description (Vector)
Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.
Gene ID
228608
Gene Name (Vector)
spermine oxidase
Gene Symbol
Smox
ORF Size (aa)
1668
ORF Size (bp)
1668 bp
RefSeq ID
NM_145533
RefSeq Synonyms
NM_145533, NM_001177840, NM_001177839, NM_001177838, NM_001177837, NM_001177836, NM_001177835, NM_001177834, NM_001177833, BC004831,
Species
mouse
UniGene ID
Mm.136586

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.