mouse SMC4 shRNA silencing AAV

Name 
AAV-m-SMC4-shRNA
Cat No 
shAAV-272631
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Smc4.

shAAV-272631
AAV-m-SMC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Smc4 (structural maintenance of chromosomes 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2500002A22Rik; C79747; SMC-4; Smc4l1
Description (Vector)
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Gene ID
70099
Gene Name (Vector)
structural maintenance of chromosomes 4
Gene Symbol
Smc4
ORF Size (aa)
3651
ORF Size (bp)
3651 bp
RefSeq ID
NM_133786
RefSeq Synonyms
NM_133786, BC062939, BC061481,
Species
mouse
UniGene ID
Mm.206841

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.