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mouse SMC3 shRNA silencing AAV

Name 
AAV-m-SMC3-shRNA
Cat No 
shAAV-272629
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Smc3.

shAAV-272629
AAV-m-SMC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Smc3 (structural maintenance of chromosomes 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Bamacan; Cspg6; HCAP; Mmip1; SMC-3; SmcD
Description (Vector)
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Gene ID
13006
Gene Name (Vector)
structural maintenance of chromosomes 3
Gene Symbol
Smc3
ORF Size (aa)
3651
ORF Size (bp)
3651 bp
RefSeq ID
NM_007790
RefSeq Synonyms
NM_007790, BC062935, BC057345,
Species
mouse
UniGene ID
Mm.14910

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.