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mouse SLC9A3R1 shRNA silencing AAV

Name 
AAV-m-SLC9A3R1-shRNA
Cat No 
shAAV-272530
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Slc9a3r1.

shAAV-272530
AAV-m-SLC9A3R1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc9a3r1 (solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EBP-50; NHE-RF; NHERF-1; NHERF1
Description (Vector)
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules.
Gene ID
26941
Gene Name (Vector)
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Gene Symbol
Slc9a3r1
ORF Size (aa)
1068
ORF Size (bp)
1068 bp
RefSeq ID
NM_012030
RefSeq Synonyms
NM_012030, BC085141,
Species
mouse
UniGene ID
Mm.27842

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.