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mouse SLC7A6 shRNA silencing AAV

Name 
AAV-m-SLC7A6-shRNA
Cat No 
shAAV-272515
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Slc7a6.

shAAV-272515
AAV-m-SLC7A6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc7a6 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI643885; LAT-2; LAT3
Description (Vector)
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Gene ID
330836
Gene Name (Vector)
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
Gene Symbol
Slc7a6
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
RefSeq ID
NM_178798
RefSeq Synonyms
NM_178798, BC038404,
Species
mouse
UniGene ID
Mm.46749

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.