mouse SLC5A12 shRNA silencing AAV

Cat. No: shAAV-272458

Availability: 6-8 weeks

Name: AAV-m-SLC5A12-shRNA

This is an AAV expressing shRNA for silencing of Mouse Slc5a12.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Slc5a12
Gene Name: solute carrier family 5 (sodium/glucose cotransporter), member 12
Gene ID: 241612
Gene Synonyms: AI315119; D630015G19; SMCT2
ORF Size: 1860 bp
RefSeq#: NM_001003915
Gene Description: Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity).
UniGene ID: Mm.277148