mouse SLC46A1 shRNA silencing AAV

Name
AAV-m-SLC46A1-shRNA

Cat No
shAAV-272435

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Slc46a1.

shAAV-272435

AAV-m-SLC46A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Slc46a1 (solute carrier family 46, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110002C08Rik; D11Ertd18e; HCP1; Pcft

Description (Vector)

Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.

Gene ID

52466

Gene Name (Vector)

solute carrier family 46, member 1

Gene Symbol

Slc46a1

ORF Size (aa)

1380

ORF Size (bp)

1380 bp

RefSeq ID

NM_026740

RefSeq Synonyms

NM_026740, BC057976,

Species

mouse

UniGene ID

Mm.131618

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.